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Focal Segmental Glomerulosclerosis, can be reversed at the early stage. We offer the overview of FSGS basics, treatment, Symptoms ﹠ Complication and Healthy Livings.

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What is the Basics of FSGS?

What is Focal segmental glomerulosclerosis (FSGS)?

Focal segmental glomerulosclerosis (FSGS) is scar tissue that forms in parts of the kidney called glomeruli. The glomeruli serve as filters, helping get rid of the body of unnecessary or harmful substances. Each kidney has thousands of glomeruli. One glomeruli is called a glomerulus. "Focal" means that some of the glomeruli become scarred, while others remain normal. "Segmental" means that only part of an individual glomerulus is damaged.

Focal segmental glomerulosclerosis (FSGS) is a cause of nephrotic syndrome in children and adolescents, as well as an important cause of kidney failure in adults. It is also known as "focal glomerular sclerosis" or "focal nodular glomerulosclerosis."

What does FSGS mean?

Sclerosis means “Scarring.” There are millions of tiny, microscopic filters in the kidneys called “glomeruli.” They are filters much like a sieve you might find in your kitchen, and they filter the blood, taking out the water-like part that becomes urine and leaving the protein in the blood. If the glomeruli become scarred, then they stop doing a good job filtering the blood and protein starts leaking into the urine instead of staying in the blood. The word “focal” is added because in FSGS, only some of the glomeruli filters become scarred. “Segmental” means that only some sections of the glomerulus becomes scarred, just parts of them. So Focal Segmental Glomerulosclerosis means:

Focal = some

Segmental = sections

Glomerulo = of kidney filters

Sclerosis = are scarred

What causes FSGS?

FSGS (focal segmental glomerulosclerosis) is a genetic abnormality that affects glomerulus of the kidneys. The scar tissue covers the body's filtration system, and it can lead to chronic renal failure. FSGS is “idiopathic,” which means it arises without a known cause. The causes of FSGS are largely unknown, but advances in clinical studies link the disease to reflux nephropathy. Another cause of FSGS includes the abnormal length of the ureter that extends into the bladder.

Each person has two kidneys in their lower back. Each kidney is made up of approximately one million tiny filters called “glomeruli.” Much as a coffee filter keeps coffee grounds in, glomeruli keep valuable cells and protein in the blood. When glomeruli become damaged, proteins begin leaking into the urine (proteinuria). Proteinuria causes fluid to accumulate in the body, and prolonged leakage can lead to kidney damage and even failure. Focal Segmental Glomerulosclerosis (FSGS) is a rare disease that attacks the kidney’s filtering system (glomeruli) causing serious scarring.



Next:Will Pregnancy Affect FSGS?

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