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Focal Segmental Glomerulosclerosis, can be reversed at the early stage. We offer the overview of FSGS basics, treatment, Symptoms ﹠ Complication and Healthy Livings.

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What Cause FSGS?

What Cause FSGS?Focal Segmental Glomerulosclerosis (FSGS) is a rare disease that attacks the kidney’s filtering system (glomeruli) causing serious scarring. FSGS is one of the causes of a serious condition known as Nephrotic Syndrome. But what cause FSGS?

The causes of FSGS are largely unknown which is not caused by a single disease. It has several different causes. The scarring may be the result of an infection, or drug toxicity, or a disease that affects the entire body, like diabetes, HIV infection, sickle cell disease or lupus disease. Sometimes, there is no apparent associated disease or cause. There may be a genetic component in some people. People with these conditions may develop glomerulosclerosis:

1. Glomerulonephritis, an inflammation of the glomeruli. About 7 to 15% of people with glomeruonephritis (inflammation) develop glomerulosclerosis (scarring)

2. Reflux nephropathy (backward flow of the urine up to the kidney).

3. Kidney-harming chemicals or medicines that damage the glomeruli.

For example reflux nephropathy is a condition in which kidneys are damaged from a backward influx of urine into the kidney. Valves that connect the kidney to the ureter evolved to keep urine flow in a one-way direction. However, genetic abnormalities damage these valves, allowing urine to relay back into the effected kidney. Because there is more pressure contained in the bladder, the urine that is returned to the kidney causes scarring after prolonged exposure without treatment.

Other causes of FSGS involve the abnormal length of the ureter that extends into the bladder. Normally, the ureter is buried well into the bladder with a genetically programmed length. When abnormalities in bladder tunnels are present, the pressure in the bladder overcomes the closed structure and pushes urine back into the kidneys. A shortened ureter also facilitates the opened tunnels giving way to the pressure.

In all, no matter what cause the FSGS, we should focus on the damaged kidney and aim at repairing the kidney and recovering the kidney function. If you want to know more information about FSGS causes and treatment, you can leave a message below or you can email us igacure@gmail.com.

Hope the above information is helpful for you. If you have any other questions on kidney disease or want to get more personalized and professional treatment suggestions, please leave a message below.







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