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Focal Segmental Glomerulosclerosis, can be reversed at the early stage. We offer the overview of FSGS basics, treatment, Symptoms ﹠ Complication and Healthy Livings.

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What Does FSGS Prognosis Mean?

What does FSGS Prognosis mean?Focal segmental glomerulosclerosis (FSGS) is a kind of kidney disease among adults and children, a histologic diagnosis that may be found either without an identifiable cause (in which case it is called "idiopathic" or "primary") or in response to previous glomerular injury, glomerular hypertension, or hypertrophy ("secondary"). If patients with FSGS progress, then it may show Nephrotic Syndrome and even ESRD, which is one of the most concerns among people.

Now I would like to give a brief introduction of FSGS prognosis. Prognosis — The potential efficacy of therapy must be considered in relation to the natural history of the disease. Untreated primary FSGS often follows a progressive course to end-stage renal disease (ESRD). The rate of spontaneous complete remission among patients with nephrotic syndrome is unknown, but is probably less than 10 percent. Spontaneous remission is more likely to occur among patients with normal kidney function and non-nephrotic proteinuria. Previously, treatment was not considered to substantially improve the prognosis of FSGS. However, longer courses of treatment have resulted in response rates of up to 70 percent and improved overall prognosis. Whether the outcome of patients who present with a substantial reduction in kidney function can be altered is less clear.

Prognostic factors — Factors that appear to influence response to treatment and/or prognosis principally include degree of proteinuria, renal dysfunction, histologic findings, and the response to therapy.

Degree of proteinuria — Patients with the nephrotic syndrome (proteinuria ≥3.0 or 3.5 g/day and low plasma albumin concentration) have five-year renal survival rates of 60 to 90 percent, and 10-year renal survival rates of 30 to 55 percent . Massive proteinuria (>10 g/day), when unresponsive to treatment, is associated with an even worse prognosis, with most patients progressing to ESRD within five years.

Severity of renal dysfunction — More severe renal dysfunction at present is generally associated with worse renal survival. If you want to know more details about FSGS prognosis, you can leave a message or email us to igacure@gmail.com.

Hope the above information is helpful for you. If you have any other questions on kidney disease or want to get more personalized and professional treatment suggestions, please leave a message below.







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