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FSGS

Focal Segmental Glomerulosclerosis, can be reversed at the early stage. We offer the overview of FSGS basics, treatment, Symptoms ﹠ Complication and Healthy Livings.

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Is FSGS the Result of Immune Complexes Injury

Is FSGS the Result of Immune Complexes InjuryFocal Segmental Glomerulosclerosis (FSGS) is a kidney disorder in which your glomeruli become scarred gradually. An immune complexes is formed from the intergral binding of an antibody to a soluble antigen. When you are under immunofluorescence examination, you will find that in the scared part of glomeruli, there deposits some immune complexes, such as C3, IgM and C1q. Is FSGS the result of immune complexes injury? Go on reading to learn more information.

Immune complexes indeed can cause kidney injury for FSGS patients.

When your immune system is poor, bacteria and virus can enter your body and then a lot of antibodies are secreted to fight against those antigens. During this course, massive immune complexes come into being. With blood circulation, immune complexes flow into kidneys and deposit. For kidneys, those immune complexes are antigens, so they secrete cytokines to cleanse them from the kidneys, leading to kidney inflammation. Aggressive kidney inflammatory response can cause kidney injury.

How to prevent immune complexes from injuring your kidneys with FSGS?

Conventional treatment for FSGS is to use steroid and other immunosuppressants to block kidney inflammation and prevent further kidney damage, but they can not cleanse those immune complexes from the kidneys. Immunotherapy may be a good choice for you. It can cleanse the cycling immune complexes and inflammatory chemicals from the blood to eliminate kidney inflammation. It can also block inflammatory reaction and increase the kidneys’ tolerance to immune complexes so as to prevent kidney inflammation. Besides, it can strengthen your immune system to prevent bacteria and virus entering into your body. After a period of treatment, your kidney function can be promoted to certain extent.

Is FSGS the result of immune complexes injury? Yes, it is. Therefore, it is necessary for you to cleanse those immune complexes as early as possible. For more information about FSGS, please leave a message below or consult online doctor.

Hope the above information is helpful for you. If you have any other questions on kidney disease or want to get more personalized and professional treatment suggestions, please leave a message below.

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