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Focal Segmental Glomerulosclerosis, can be reversed at the early stage. We offer the overview of FSGS basics, treatment, Symptoms ﹠ Complication and Healthy Livings.

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What Affects the Prognosis of FSGS

What Affects the Prognosis of FSGSFocal Segmental Glomerulosclerosis (FSGS) is a kidney disease that can lead to kidney failure quickly. What affects the prognosis of FSGS? Not a few patients want to find the answer. Now let’s have a quick look.

Urine protein

If your urine protein is more than 10g/24h, FSGS develops quickly. It is likely for you to have kidney function impairment within 6 years. If your urine protein is 3-3.5 g/24h, there is 50% possibility for you to have ESRD in 6-8 years. If your urine protein is less than 3g/24h, your kidneys may still work normally after 10 years.

Treatment response

Steroids and other immunosuppressants are the common used drugs for FSGS patients to inhibit kidney inflammation and reduce protein leakage. If you are sensitive to those medications and you may get complete remission, there is 15% possibility for you to have kidney failure. Otherwise, you may have 85% possibility to develop to kidney failure.


For adult patients, they may have a better prognosis than the children. It is said that 55% FSGS adult patients have Nephrotic Syndrome and 15% of them have frequent relapse, while for children, 76% of them have Nephrotic Syndrome and 80% of them have relapse.


Black people may have a higher morbidity than the white. And they usually have a poor prognosis. 78% of black people progress to ESRD in 8.5 years, while there are only 33% white people.

High blood pressure

High blood pressure is also a factor that affects the prognosis of FSGS, because it can speed up glomerulosclerosis. If you can not control blood pressure well, you will have a poor prognosis.

Renal pathology

If your kidneys have been severely damaged or if you have Membranous Nephropathy, mesangial proliferative Nephropathy, or blood vessel impairment, it is likely for you to enter kidney failure quickly.

What affects the prognosis of FSGS? We can not change our rate, age and renal pathology, but we can reduce urine protein, lower blood pressure and choose a suitable treatment plan for FSGS so as to improve prognosis. For more information, please leave a message below or send emails to igacure@gmail.com.

Hope the above information is helpful for you. If you have any other questions on kidney disease or want to get more personalized and professional treatment suggestions, please leave a message below.







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