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How to Control Blood Pressure and Creatinine Level for IgA Nephropathy Patients

Question: My sister is suffering from IgA Nephropathy. Her creatinine is 3.1 and her blood pressure is 140/90 even with antihypertensives, mild proteinuria with microscopic hematuria. As we are not happy with the treatment as her blood pressure is not coming down nor her creatinine. What will you advise regarding this doctor?

How to Control Blood Pressure and Creatinine Level for IgA Nephropathy PatientsAnswer: IgA Nephropathy is a kind of primary glomerular nephritis characterized by the deposition of IgA and its immune complexes in mesangial areas. This can cause inflammatory reaction in the kidneys, which over time leads to impairment to the mesangial cells. And then red blood cells and protein leak into her urine.

How to lower blood pressure?

She has high blood pressure even with antihypertensives. If the blood pressure is not under control, it will further damage kidneys and even increase her risk of heart disease, which may threaten her life. In this case, some western medicine like CCB( including plendic, adalat) are often prescribed to reduce her blood pressure. ARB and ACEI are also often used to control blood pressure, but when creatinine level is more than 3, ARB (such as losartan and valsartan) and ACEI (such as captopril and enalapril) may reduce blood perfusion so as to increase creatinine level further, so the patient had better avoid such kinds of medicine.

How to lower creatinine level?

Creatinine is the by-product of muscle contraction and a small part is from the meat we consume. In diet, she should limit the intake of meat. She should also avoid strenuous exercise to reduce muscle contraction. Besides, Ketosteril and low protein diet can also help lower creatinine level.

However, to repair the damaged kidneys and improve kidney function is the fundamental solution. Because IgA Nephropathy is an autoimmune disease, we should start from the immune system. Immunotherapy can block abnormal inflammatory reaction in the kidneys and strengthen immune system to help you fight against disease.

A systemic treatment can help you control all these symptoms and live a normal life. If you want some more suggestion on diet and treatment, please send her current condition in detail to igacure@gmail.com.

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