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Can Prednisolone Cause Ankle Swelling for IgA Nephropathy Patients

Question: I have IgA Nephropathy. After taking 50 mg prednisolone for 6 weeks, my 24 hour urinary protein has reached up to 0.3. But my doctor has said me to continue medicine 45 mg. The second thing is that my ankles are swelling badly. Is this effect of prednisolone?

Can Prednisolone Cause Ankle Swelling for IgA Nephropathy PatientsAnswer: Prednisolone is a common used western medicine for IgA Nephropathy patients to treat proteinuria. As we can see that after taking prednisolone, proteinuria is gradually under control. But it can not be stopped immediately, only little by little. Because this kind of medicine is just to inhibit the kidney inflammation by decreasing immune reaction, while IgA, immune complexes and some other inflammatory factors remain in the kidneys. If you stop prednisolone suddenly, inflammatory reaction will come back soon and proteinuria will increase as well.

Though prednisolone takes effect quickly on controlling symptoms, it has many side effects if used for long term, one of which is ankle swelling. Besides, you may have muscle pain, irregular heartbeat, unusual weight gain, infection, etc.

As for IgA Nephropathy, in order to reduce the bad effect caused by prednisolone, we prefer to use the joint therapy of Chinese herbal therapies and western medicine. They can make up the respective shortcomings. Immunotherapy is such a kind of therapy. It can cleanse waste, including toxins, immune complexes and these inflammatory factors from the blood to reduce inflammation in the kidneys. It can also block the abnormal immune reaction and increase the kidneys’ tolerance to the deposited IgA and immune complexes, which can prevent relapse of inflammation. Moreover, it can set up a good blood environment for kidney self-healing. After a period of treatment, proteinuria and swelling will disappear. Creatinine level, BUN, GFR will also be improved. Long-term treatment with Immunotherapy, you can achieve a good curative effect.

Do you get the answer you want to know? If not, please feel free to contact online doctor. We are glad to help you make a personalized treatment plan.

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