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IgA Nephropathy, Proteinuria Gets Relapse Frequently: What Causes It

IgA Nephropathy, Proteinuria Gets Relapse Frequently: What Causes ItThe occurrence of proteinuria means that kidney filtration function is impaired. To avoid too much kidney damage by proteinuria, you should take treatment timely to stop proteinuria. For IgA Nephropathy patients, proteinuria gets relapse frequently. What causes it?

-Inflammation in the kidney is not completely eliminated.

A variety of factors lead to renal inflammatory response, and a large accumulation of immune complexes, leading to kidney function impairment. To prevent further impairment of renal function, the inflammatory response must be suppressed. Inflammation is so active that glomerular filtration becomes worse, leading to more proteinuria. Therefore, the treatment of proteinuria should first identify the location of renal inflammation, and then in symptomatic treatment, reducing protein leakage.

-Frequent infection stealthily erodes kidney function.

People with kidney disease have lower immunity and resistance than the general population, so it is easy to cause various infections, such as respiratory tract infection, colds and fever; oral infection such as periodontitis; In addition, there are urinary tract infections such as kidney stones and hydronephrosis. Infections can cause an immune inflammatory response that increases toxin accumulation, which is not conducive to renal function protection. To reduce proteinuria, these infectious factors should be avoided as much as possible.

-Drug abuse leads to deterioration of kidney function.

The commonly used drugs of lowering proteinuria include hormone, immunosuppressant, ACEI or ARBs. Taking the medicine strictly according to the doctor's instruction will have better curative effect, but if taking the medicine carelessly, it will easily produce side effect. For example, ACEI and ARBs have the effect of promoting creatinine, which is not suitable for patients with renal insufficiency and advanced stage. Drug abuse will only aggravate the condition.

Now you know the three common causes of proteinuria for IgA Nephropathy patients. Hope you pay attention to them in the daily and reduce the relapse as much as possible. For more information on IgA Nephropathy, please leave a message below or contact online doctor.

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