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Is It Possible for IgA Nephropathy Patients to Avoid Dialysis

Question: I have IgA Nephropathy. I am currently on dialysis. My creatinine is at 4 and my BUN is at 10. They found 70 % scar tissue damage in my biopsy. Is it possible for me to avoid dialysis?

Is It Possible for IgA Nephropathy Patients to Avoid DialysisAnswer: Dialysis may be the most common used kidney replacement therapy for kidney failure patients to remove waste and excess fluid from the blood. From what you said, we can see that your BUN is well controlled by dialysis within the normal level (7-20 mg/dL) and your creatinine level is still a little higher than the normal level (0.5-1.2 mg/dL). If you stop dialysis now, BUN and creatinine level will go up again. If you want to avoid dialysis, you should improve kidney function.

You said that 70 % scar tissue damage, which indicates that there are 30 % kidney tissues possible for you to improve kidney function. Among the 30 % kidney tissues, some are in a state of inflammation and some are intact. If you can take proper measures to repair the inflammatory part, you can recover 30 % kidney function and then you can live a much better life than now.

Considering that IgA Nephropathy is an immunodeficiency disease, we should start treatment from the immune system. Immunotherapy is recommended. It has six steps, including accurate diagnosis, immune clearance, immune blocking, immune tolerance, immune regulation and immune protection. Because of the declined kidney function, a lot of toxins, immune complexes and metabolic waste build up in the blood. During immune clearance, dialysis, immune absorption, plasma exchange, blood perfusion and some other therapies may be used together to remove the waste from the blood. The curative effects achieved by the combined therapies are much better than dialysis alone. The other steps of Immunotherapy can block the abnormal immune reaction and inhibit the inflammation. Besides, they can provide nutrients for the kidney tissues to repair themselves.

After a period of treatment, dialysis frequency can be reduced. Long-term treatment can help you avoid dialysis. And the earlier you receive treatment, the more possibility for you to avoid dialysis. If all of the tissues are scarred, there is no chance.

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