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BUN 48, Creatinine 4.6, BP 130/80 with IgA Nephropathy: Which Can Save My Life

Question: I am suffering from IgA Nephropathy since 20 years. My BUN is 48, creatinine is 4.6, bp is 130/80. I am taking medicines for BP control only and iron tablets only. Please advise which can save my life.

BUN 48, Creatinine 4.6, BP 130/80 with IgA Nephropathy: Which Can Save My LifeAnswer: To be sincerely, your illness is not good. Your BUN is 48 and creatinine is 4.6, which means more than 50 % of kidney function has been damaged. Your blood pressure is 130/80, which is a little higher. High blood pressure also results from the impaired kidney function. According to the GFR, IgA Nephropathy is divided into 5 stages. I think you are in the stage 4. If you can not control the state of illness, you may have to take dialysis. Therefore, it is urgent for you to take the prompt treatment to improve kidney function and avoid dialysis.

Now let’s learn more about IgA Nephropathy first.

As we all know, IgA Nephropathy is a kind of auto immune disease. Because of the poor immune system, your body can not fight against bacteria or virus that invade into your body. They may further cause immune disorder and overreaction of immune system. During this process, massive immune complexes will be produced and come into the blood. With blood circulation, these immune complexes come into the kidneys and deposit on the glomerulus basement membrane, which will cause the proliferation and swelling of mesangial cells so as to damage their charge barrier and mechanical barrier. As a result, they can not block the leakage of red blood cells and protein. That is why so many patients have blood urine or protein urine.

Treatment suggestion for IgA Nephropathy patients with BUN 48, creatinine 4.6 and bp 130/80

-Block the abnormal immune reaction

-Remove the immune complexes from the kidneys

-Repair the damaged mesangial cells

Immunosuppressants can help you inhibit inflammation and control symptoms, but it is not enough. Immunotherapy is helpful, because it can help you achieve the above goals. If you would like to know more information about this therapy, please contact online doctor.

Though you are in stage 4, it is possible for you to live a normal life with aggressive treatment. And the earlier you receive treatment, the more possibility for you to reverse it.

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Hope the above information is helpful for you. If you have any other questions on kidney disease or want to get more personalized and professional treatment suggestions, please leave a message below.

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