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How to Stop Protein Leakage in Urine with IgA Nephropathy

How to Stop Protein Leakage in Urine with IgA Nephropathy“Hi, I am diagnosed with IgA Nephropathy and my protein in 24 hours urine is 360mg after I done protein leakage. How can I stop protein leakage in my urine?” This is a message left in our website last night. Protein leakage is not a rate condition for IgA Nephropathy patients, but a common clinical manifestation. Medicines like prednisone and some hypotensive drugs indeed help to reduce protein in urine, but unfortunately, they are not permanent cure.

How is protein leakage caused in IgA Nephropathy?

Protein is an important ingredients in our blood. While flowing through kidney with blood, it is kept in our body by the charger barrier and mechanical barrier of glomerulus, a kidney tissue. However, when glomeruli are damaged and can not do this job properly, protein leak into urine while flowing through kidney. As a result, proteinuria is formed.

In IgA Nephropathy, glomeruli are damaged due to IgA deposition in mesangial area. IgA stands for Immunoglobulin A which is an antibody and help us fight against harmful substances in normal condition. However, for IgA Nephropathy patients, due to immune disorder, large amounts of IgA are formed in the body. They circulate with blood and deposit in mesangial area while passing through kidney. This condition causes severe inflammation in kidney, which damage surrounding kidney tissues. Protein leakage occurs when glomeruli are damaged due to persistent inflammation.

How to stop protein leakage in urine with IgA Nephropathy

Protein leakage is a clinical manifestation of IgA Nephropathy, not a cause of kidney damages. In many countries, immunosuppressive agents are used to block inflammation in kidney, which helps to reduce protein leakage. However, as IgA deposition in kidney is not removed and meanwhile injured glomeruli are not repaired timely, protein leakage relapses when patients stop taking medicine or reduce medicine dose.

To stop protein leakage in urine permanently, we need to normalize immune system, clear IgA deposition away from blood and kidney, repair injured glomeruli and block inflammation in kidney. Only when all these medical goals are achieved, can further kidney damages are avoided and also can protein leakage is stopped fundamentally.

Immunotherapy is a treatment that is commonly used to help IgA Nephropathy patients in our hospital. It is not a simply medicine, but a combination of western medicine and Chinese medicine. We know Chinese medicine and western medicine work differently and also they show different treatment effects. By combining them properly, we can stop protein leakage from root. Besides, in this treatment, medicines that can cause side effects are used temporarily and then replaced with natural remedies when we achieve our treatment goals. For this reason, no side effects are caused during the whole treatment process. Therefore, immunotherapy is a natural treatment to help IgA Nephropathy patients stop protein leakage in urine.

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Hope the above information is helpful for you. If you have any other questions on kidney disease or want to get more personalized and professional treatment suggestions, please leave a message below.







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