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IgA Nephropathy

You are here because you know someone with IgA Nephropathy. This section covers information related questions and concerns of IgA Nephropathy basics, treatments, symptoms and healthy living.

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Why Pleural Effusion Can Occur in Nephrotic Syndrome

Why Pleural Effusion Can Occur in Nephrotic SyndromeMany Nephrotic Syndrome patients have edema. In the early stage, edema may only appear in eyelid and face. With the development of Nephrotic Syndrome, it appears in ankles and legs. Some patients may even have pleural effusion and peritoneal effusion. Pleural effusion is a buildup of fluid in chest or on the lungs. Why pleural effusion can occur in Nephrotic Syndrome?

Generally speaking, there are two causes:

-Plasma colloid osmotic pressure decline

Plasma colloid osmotic pressure is maintained by albumin in the plasma. When epithelial cells of glomeruli and filtration barrier are damaged, massive albumin leaks into the urine, leading to hypoproteinemia. This can cause decline of plasma colloid pressure. When the pressure decreases to certain extent, fluid in blood vessels shifts into the tissue space, causing edema. The severity of edema is closely associated with plasma colloid osmotic pressure.

-Fluid and sodium retention

When fluid flows into tissue space, blood volume reduces. In order to restore blood volume, your body will secrete more antidiuretic hormone, which increases the ability of renal tubule to absorb fluid. On the other hand, renin-angiotensin-aldosterone system (RAAS) is activated. Angiotensin can stimulate proximal tubule to reabsorb NaCl so as to reduce NaCl discharge. It can also stimulate the synthesis and release of aldosterone and regulate distal convoluted tubule and collecting tube to transport Na and potassium. Besides, it stimulates the release of vasopressin and increases the distal convoluted tubule and collecting tube’s reabsorption to water so as to cause less urine output and swelling.

When pleural effusion appears, you should take treatment as early as possible to prevent heart failure, respiratory failure and some other severe complications. In Shijiazhuang Kidney Disease Hospital, there are many therapies to help you, such as Micro-Chinese Medicine Osmotherapy, Medicated Bath, Mai Kang and decoction. They help repair the damaged kidneys and improve kidney function so as to relieve edema and other body malaise.

Why pleural effusion can occur in Nephrotic Syndrome? The above is the general explanation. For more information, please contact online doctor or leave a message below.

Hope the above information is helpful for you. If you have any other questions on kidney disease or want to get more personalized and professional treatment suggestions, please leave a message below.

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