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IgA Nephropathy

You are here because you know someone with IgA Nephropathy. This section covers information related questions and concerns of IgA Nephropathy basics, treatments, symptoms and healthy living.

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What Causes the Massive Edema of Nephrotic Syndrome

What Causes the Massive Edema of Nephrotic SyndromeMassive edema is a main clinical manifestation of Nephrotic Syndrome. What causes the massive edema of Nephrotic Syndrome? If you want to know the answer, the following information may be helpful for you.

Glomeruli and renal tubule function disorder

Under normal circumstance, fluid, sodium and so on is filtered out of glomeruli. But almost 99 % of them can be reabsorbed by renal tubule so as to keep the dynamic balance of electrolytes. When your kidneys go wrong, your glomeruli can not remove the fluid and sodium out, while your renal tubules still play their role in reabsorption. In such case, water and sodium retains in your body, leading to edema.

Heavy proteinuria

Heavy proteinuria is also a common cause of edema for Nephrotic Syndrome. Because when a lot of protein leaks into urine, protein in blood decreases, resulting in declined plasma colloid osmotic pressure. And then fluid flows into tissue space, leading to massive edema.

Other complications

-According to Traditional Chinese Medicine theory, kidney and liver are closely associated. When your kidneys are severely damaged, your liver can not function very well. Liver disease is also a contributor to swelling.

-When your kidney function impairs, your kidneys can not secrete enough erythropoietin to make red blood cells, leading to anemia. Anemia causes ischemia and anoxia in the kidneys. And then your kidneys secrete renin to raise blood pressure. Anemia, high blood pressure, accumulated waste products and declined immunity can cause secondary cardiac insufficiency. It gives rise to edema as well.

What causes the massive edema of Nephrotic Syndrome? I think you have had a clear mind about this question. If you still have any question, please feel free to contact online doctor or leave a message below. After analyzing your case, we will contact you.

Hope the above information is helpful for you. If you have any other questions on kidney disease or want to get more personalized and professional treatment suggestions, please leave a message below.







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